BDBM50403171 CHEMBL278981
SMILES: CN1C2CCc3cc(Br)ccc3C2CCC1=O
InChI Key: InChIKey=IOIQUYFYVVEHRE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5α-Reductase 1 (5α-R1) (Homo sapiens (Human)) | BDBM50403171![]() (CHEMBL278981) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory concentration required to inhibit Steroid 5-alpha-reductase type 1 in cultured Hs 68 human foreskin fibroblast cells | Bioorg Med Chem Lett 3: 1157-1162 (1993) Article DOI: 10.1016/S0960-894X(00)80306-6 BindingDB Entry DOI: 10.7270/Q2VD70NP | |||||||||||
More data for this Ligand-Target Pair |