BDBM50403383 CHEMBL280457

SMILES: Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccc(cc1)-c1nc(=O)o[nH]1

InChI Key: InChIKey=DVSUMKGRJWSZJG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50403383 (CHEMBL280457) Show SMILES Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C22H14FN5O2/c23-17-7-5-13(6-8-17)18-19(14-9-11-24-12-10-14)26-20(25-18)15-1-3-16(4-2-15)21-27-22(29)30-28-21/h1-12H,(H,25,26)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytes				Bioorg Med Chem Lett 5: 1171-1176 (1995) Article DOI: 10.1016/0960-894X(95)00189-Z BindingDB Entry DOI: 10.7270/Q28S4PV1
					More data for this Ligand-Target Pair