BDBM50403403 CHEMBL16926

SMILES: CN1CCC(CC1)S(=O)(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=IXEJTYMWNGQTPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50403403 (CHEMBL16926) Show SMILES CN1CCC(CC1)S(=O)(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C26H25FN4O2S/c1-31-16-12-23(13-17-31)34(32,33)22-8-4-20(5-9-22)26-29-24(18-2-6-21(27)7-3-18)25(30-26)19-10-14-28-15-11-19/h2-11,14-15,23H,12-13,16-17H2,1H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytes				Bioorg Med Chem Lett 5: 1171-1176 (1995) Article DOI: 10.1016/0960-894X(95)00189-Z BindingDB Entry DOI: 10.7270/Q28S4PV1
					More data for this Ligand-Target Pair