BDBM50403467 CHEMBL4162963

SMILES: Cl.Cl.C[C@@H](O)[C@H](N)C(=O)NCc1cccc(CNC(C)=N)c1

InChI Key: InChIKey=RJBXDYQFSZSRDW-LEWJYISDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50403467 (CHEMBL4162963) Show SMILES Cl.Cl.C[C@@H](O)[C@H](N)C(=O)NCc1cccc(CNC(C)=N)c1 |r| Show InChI InChI=1S/C26H39N5O5/c1-16(2)12-20(31-25(36)29-15-26(3,4)5)24(35)30-21(23(34)27-11-10-22(32)33)13-17-14-28-19-9-7-6-8-18(17)19/h6-9,14,16,20-21,28H,10-13,15H2,1-5H3,(H,27,34)(H,30,35)(H,32,33)(H2,29,31,36)/t20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...				Eur J Med Chem 152: 53-64 (2018) Article DOI: 10.1016/j.ejmech.2018.04.027 BindingDB Entry DOI: 10.7270/Q2C2500M
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