BDBM50403470 CHEMBL4172371

SMILES: Cl.Cl.CSCC[C@H](N)C(=O)NCc1cccc(CNC(C)=N)c1

InChI Key: InChIKey=SSLBUOVBFKPQMF-FCHUYYIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50403470 (CHEMBL4172371) Show SMILES Cl.Cl.CSCC[C@H](N)C(=O)NCc1cccc(CNC(C)=N)c1 |r| Show InChI InChI=1S/C26H37N5O5/c1-17(2)14-21(30-26(36)31-12-6-3-7-13-31)25(35)29-22(24(34)27-11-10-23(32)33)15-18-16-28-20-9-5-4-8-19(18)20/h4-5,8-9,16-17,21-22,28H,3,6-7,10-15H2,1-2H3,(H,27,34)(H,29,35)(H,30,36)(H,32,33)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...				Eur J Med Chem 152: 53-64 (2018) Article DOI: 10.1016/j.ejmech.2018.04.027 BindingDB Entry DOI: 10.7270/Q2C2500M
					More data for this Ligand-Target Pair