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SMILES: CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)[C@H](S)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O

InChI Key: InChIKey=AFEXYTZJFRSLAP-KAWFJRQCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50403479
PNG
(CHEMBL2115457)
Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)[C@H](S)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O
Show InChI InChI=1S/C28H44N6O6S2/c1-16(2)22(32-25(37)26(41)33-23(35)19(30)10-6-7-12-29)27(38)34-15-18-9-5-4-8-17(18)14-21(34)24(36)31-20(28(39)40)11-13-42-3/h4-5,8-9,16,19-22,26,41H,6-7,10-15,29-30H2,1-3H3,(H,31,36)(H,32,37)(H,33,35)(H,39,40)/t19-,20-,21-,22-,26-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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PC sid
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Similars
Article
n/an/a 20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of farnesyl transferase (FTase) of rat brain

Bioorg Med Chem Lett 5: 1779-1784 (1995)


Article DOI: 10.1016/0960-894X(95)00314-J
BindingDB Entry DOI: 10.7270/Q2H41RDH
More data for this
Ligand-Target Pair