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SMILES: CNCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=MYNBDDBMGFGOJU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50403676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50403676 (CHEMBL86522) Show SMILES CNCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C13H14F3N3/c1-17-6-5-11-8-18-12(19-11)9-3-2-4-10(7-9)13(14,15)16/h2-4,7-8,17H,5-6H2,1H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	0.912	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Contractile effects antagonized by mepyramine (0.3-100 nM) against Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50403676 (CHEMBL86522) Show SMILES CNCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C13H14F3N3/c1-17-6-5-11-8-18-12(19-11)9-3-2-4-10(7-9)13(14,15)16/h2-4,7-8,17H,5-6H2,1H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileum				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50403676 (CHEMBL86522) Show SMILES CNCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C13H14F3N3/c1-17-6-5-11-8-18-12(19-11)9-3-2-4-10(7-9)13(14,15)16/h2-4,7-8,17H,5-6H2,1H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	0.832	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Compound was tested for the contractile effects antagonized by mepyramine (1-1000 nM) against Histamine H1 receptor of guinea pig aorta.				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM50403676 (CHEMBL86522) Show SMILES CNCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C13H14F3N3/c1-17-6-5-11-8-18-12(19-11)9-3-2-4-10(7-9)13(14,15)16/h2-4,7-8,17H,5-6H2,1H3,(H,18,19)	MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against M3-acetylcholine receptor of guinea pig ileum.				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair