BDBM50405456 CHEMBL175370

SMILES: CC(C)Cn1c2ccc3n(Cc4ccccc4)cnc3c2c(=O)n(C)c1=O

InChI Key: InChIKey=IBZKWUXHQHCWAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50405456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50405456 (CHEMBL175370) Show SMILES CC(C)Cn1c2ccc3n(Cc4ccccc4)cnc3c2c(=O)n(C)c1=O Show InChI InChI=1S/C21H22N4O2/c1-14(2)11-25-16-9-10-17-19(18(16)20(26)23(3)21(25)27)22-13-24(17)12-15-7-5-4-6-8-15/h4-10,13-14H,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 2 from pig coronary artery				J Med Chem 29: 972-8 (1986) BindingDB Entry DOI: 10.7270/Q26W9C9F
					More data for this Ligand-Target Pair