BDBM50405457 CHEMBL369824

SMILES: CC(C)Cn1c2ccc3[nH]c(nc3c2c(=O)n(C)c1=O)C(C)(C)C

InChI Key: InChIKey=ZKMVTUIQJLBZJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50405457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50405457 (CHEMBL369824) Show SMILES CC(C)Cn1c2ccc3[nH]c(nc3c2c(=O)n(C)c1=O)C(C)(C)C Show InChI InChI=1S/C18H24N4O2/c1-10(2)9-22-12-8-7-11-14(20-16(19-11)18(3,4)5)13(12)15(23)21(6)17(22)24/h7-8,10H,9H2,1-6H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 2 from pig coronary artery				J Med Chem 29: 972-8 (1986) BindingDB Entry DOI: 10.7270/Q26W9C9F
					More data for this Ligand-Target Pair