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SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6]-[#6]P([#8])(=O)[#6]P([#8])([#8])=O

InChI Key: InChIKey=AZPQJOFQZGCZIQ-BLKVHLKTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50405611   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Squalene synthase


(Rattus norvegicus)		BDBM50405611
PNG
(CHEMBL1160231)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6]-[#6]P([#8])(=O)[#6]P([#8])([#8])=O |w:13.13|
Show InChI InChI=1S/C18H34O5P2/c1-16(2)9-7-11-18(4)13-8-12-17(3)10-5-6-14-24(19,20)15-25(21,22)23/h9-10,13H,5-8,11-12,14-15H2,1-4H3,(H,19,20)(H2,21,22,23)/b17-10?,18-13+
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MMDB

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PC cid
PC sid
UniChem
PubMed
n/an/a 6.70E+4n/an/an/an/an/an/a



Squibb Institute for Medical Research

Curated by ChEMBL


Assay Description
Inhibition of squalene synthetase was determined in rat liver microsomes

J Med Chem 31: 1869-71 (1988)


BindingDB Entry DOI: 10.7270/Q2NZ88T8
More data for this
Ligand-Target Pair