BDBM50405699 CHEMBL4174798

SMILES: CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1ccc(C)cc1

InChI Key: InChIKey=HGJZUVHTFSPDPZ-SFYZADRCSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50405699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50405699 (CHEMBL4174798) Show SMILES CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1ccc(C)cc1 Show InChI InChI=1S/C11H19NO5S/c1-7(5-18)9(13)12-6-11(16-2,17-3)4-8(12)10(14)15/h7-8,18H,4-6H2,1-3H3,(H,14,15)/t7-,8+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	232	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...				Eur J Med Chem 152: 208-222 (2018) Article DOI: 10.1016/j.ejmech.2018.04.037 BindingDB Entry DOI: 10.7270/Q2B27XT0
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50405699 (CHEMBL4174798) Show SMILES CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1ccc(C)cc1 Show InChI InChI=1S/C11H19NO5S/c1-7(5-18)9(13)12-6-11(16-2,17-3)4-8(12)10(14)15/h7-8,18H,4-6H2,1-3H3,(H,14,15)/t7-,8+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	234	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...				Eur J Med Chem 152: 208-222 (2018) Article DOI: 10.1016/j.ejmech.2018.04.037 BindingDB Entry DOI: 10.7270/Q2B27XT0
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50405699 (CHEMBL4174798) Show SMILES CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1ccc(C)cc1 Show InChI InChI=1S/C11H19NO5S/c1-7(5-18)9(13)12-6-11(16-2,17-3)4-8(12)10(14)15/h7-8,18H,4-6H2,1-3H3,(H,14,15)/t7-,8+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...				Eur J Med Chem 152: 208-222 (2018) Article DOI: 10.1016/j.ejmech.2018.04.037 BindingDB Entry DOI: 10.7270/Q2B27XT0
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50405699 (CHEMBL4174798) Show SMILES CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1ccc(C)cc1 Show InChI InChI=1S/C11H19NO5S/c1-7(5-18)9(13)12-6-11(16-2,17-3)4-8(12)10(14)15/h7-8,18H,4-6H2,1-3H3,(H,14,15)/t7-,8+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in HEK293 cells harboring glosensor-22F cAMP plasmid DNA assessed as inhibition of forskolin-stimulated c...				Eur J Med Chem 152: 208-222 (2018) Article DOI: 10.1016/j.ejmech.2018.04.037 BindingDB Entry DOI: 10.7270/Q2B27XT0
					More data for this Ligand-Target Pair