BDBM50405701 CHEMBL4167588

SMILES: CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1cccs1

InChI Key: InChIKey=ZJAFSOKXFCWPPA-WXHSDQCUSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50405701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50405701 (CHEMBL4167588) Show SMILES CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1cccs1 Show InChI InChI=1S/C15H19NO5S2/c1-10(9-22)14(17)16-8-12(7-13(16)15(18)19)23(20,21)11-5-3-2-4-6-11/h2-6,10,12-13,22H,7-9H2,1H3,(H,18,19)/t10-,12+,13+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...				Eur J Med Chem 152: 208-222 (2018) Article DOI: 10.1016/j.ejmech.2018.04.037 BindingDB Entry DOI: 10.7270/Q2B27XT0
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50405701 (CHEMBL4167588) Show SMILES CN1C(Nc2ccccc2C1=O)c1cc(C)c2oc(=O)c(cc2c1)-c1cccs1 Show InChI InChI=1S/C15H19NO5S2/c1-10(9-22)14(17)16-8-12(7-13(16)15(18)19)23(20,21)11-5-3-2-4-6-11/h2-6,10,12-13,22H,7-9H2,1H3,(H,18,19)/t10-,12+,13+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in HTLA cells assessed as increase in beta-arrestin2 recruitment after overnight incubation by Tango assa...				Eur J Med Chem 152: 208-222 (2018) Article DOI: 10.1016/j.ejmech.2018.04.037 BindingDB Entry DOI: 10.7270/Q2B27XT0
					More data for this Ligand-Target Pair