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SMILES: Cc1cc(C)c(CP(O)(O)CC(=O)CC(O)=O)c(c1)-c1ccc(F)c(C)c1

InChI Key: InChIKey=QWEHYKHVAAOFMR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406120   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Rattus norvegicus (rat))		BDBM50406120
PNG
(CHEMBL99898)
Show SMILES Cc1cc(C)c(CP(O)(O)CC(=O)CC(O)=O)c(c1)-c1ccc(F)c(C)c1
Show InChI InChI=1S/C20H24FO5P/c1-12-6-13(2)18(11-27(25,26)10-16(22)9-20(23)24)17(7-12)15-4-5-19(21)14(3)8-15/h4-8,25-27H,9-11H2,1-3H3,(H,23,24)
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MMDB

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PC cid
PC sid
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PubMed
n/an/a 8.93E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of rat microsomal HMG-CoA reductase activity by 50%

J Med Chem 33: 2952-6 (1990)


BindingDB Entry DOI: 10.7270/Q22Z16Q5
More data for this
Ligand-Target Pair