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SMILES: CC(C)c1cc(C)cc(-c2ccc(F)c(C)c2)c1CCP(O)(O)CC(=O)CC(O)=O

InChI Key: InChIKey=DAKNWYVLSJWRHS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406123   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Rattus norvegicus (rat))		BDBM50406123
PNG
(CHEMBL101436)
Show SMILES CC(C)c1cc(C)cc(-c2ccc(F)c(C)c2)c1CCP(O)(O)CC(=O)CC(O)=O
Show InChI InChI=1S/C23H30FO5P/c1-14(2)20-9-15(3)10-21(17-5-6-22(24)16(4)11-17)19(20)7-8-30(28,29)13-18(25)12-23(26)27/h5-6,9-11,14,28-30H,7-8,12-13H2,1-4H3,(H,26,27)
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MMDB

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PC cid
PC sid
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Similars
PubMed
n/an/a 3.80n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of rat microsomal HMG-CoA reductase activity by 50%

J Med Chem 33: 2952-6 (1990)


BindingDB Entry DOI: 10.7270/Q22Z16Q5
More data for this
Ligand-Target Pair