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SMILES: OC(=O)CC(=O)CP(O)(=O)C=CC1=C(c2ccccc2C11CC1)c1ccc(F)cc1

InChI Key: InChIKey=RDKXFJDUYHAGHD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406125   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Rattus norvegicus (rat))		BDBM50406125
PNG
(CHEMBL419344)
Show SMILES OC(=O)CC(=O)CP(O)(=O)C=CC1=C(c2ccccc2C11CC1)c1ccc(F)cc1 |w:10.9,t:12|
Show InChI InChI=1S/C23H20FO5P/c24-16-7-5-15(6-8-16)22-18-3-1-2-4-19(18)23(10-11-23)20(22)9-12-30(28,29)14-17(25)13-21(26)27/h1-9,12H,10-11,13-14H2,(H,26,27)(H,28,29)
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PubMed
n/an/a 70n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of rat microsomal HMG-CoA reductase activity by 50%

J Med Chem 33: 2952-6 (1990)


BindingDB Entry DOI: 10.7270/Q22Z16Q5
More data for this
Ligand-Target Pair