BDBM50406281 CHEMBL145601

SMILES: COC(=O)[C@H](Nc1nc2ccccc2c(=O)o1)c1ccccc1

InChI Key: InChIKey=GSMSNVHMJNESJD-CQSZACIVSA-N

Data: 1 KI  1 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50406281 (CHEMBL145601) Show SMILES COC(=O)[C@H](Nc1nc2ccccc2c(=O)o1)c1ccccc1 Show InChI InChI=1S/C17H14N2O4/c1-22-16(21)14(11-7-3-2-4-8-11)19-17-18-13-10-6-5-9-12(13)15(20)23-17/h2-10,14H,1H3,(H,18,19)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25.1	n/a	n/a	n/a	n/a	0.000417	1.51E+4	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Component deacylation rate constant for interaction with human leukocyte elastase				J Med Chem 33: 464-79 (1990) Checked by Author BindingDB Entry DOI: 10.7270/Q2PR7X6X
					More data for this Ligand-Target Pair