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SMILES: Nc1ccc2cc(oc2c1)S(N)(=O)=O

InChI Key: InChIKey=XOQWLQCRELKNGM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406331   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))		BDBM50406331
PNG
(CHEMBL355157)
Show SMILES Nc1ccc2cc(oc2c1)S(N)(=O)=O
Show InChI InChI=1S/C8H8N2O3S/c9-6-2-1-5-3-8(14(10,11)12)13-7(5)4-6/h1-4H,9H2,(H2,10,11,12)
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n/an/a 25n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibition of human carbonic anhydrase II (0.1 nM).

J Med Chem 33: 749-54 (1990)


BindingDB Entry DOI: 10.7270/Q2K075GW
More data for this
Ligand-Target Pair