BDBM50407328 CHEMBL302150

SMILES: CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccc(NC(=O)Nc2ccccc2Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O

InChI Key: InChIKey=LRIRHXFFCRDGFC-SUECKSNHSA-N

Data: 2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50407328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50407328 (CHEMBL302150) Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccc(NC(=O)Nc2ccccc2Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O Show InChI InChI=1S/C43H45ClN8O8/c1-24-11-13-26(14-12-24)19-34(39(45)56)49-42(59)37(22-38(54)55)51-40(57)35(20-27-15-17-29(18-16-27)48-43(60)52-33-10-6-4-8-31(33)44)50-41(58)36(47-25(2)53)21-28-23-46-32-9-5-3-7-30(28)32/h3-18,23,34-37,46H,19-22H2,1-2H3,(H2,45,56)(H,47,53)(H,49,59)(H,50,58)(H,51,57)(H,54,55)(H2,48,52,60)/t34-,35?,36+,37+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Displacement of CCK-8 from human Cholecystokinin type B receptor expressing CHO cell membranes				J Med Chem 38: 207-11 (1995) BindingDB Entry DOI: 10.7270/Q28C9XF9
					More data for this Ligand-Target Pair
Cholecystokinin A receptor (Cavia porcellus)	BDBM50407328 (CHEMBL302150) Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccc(NC(=O)Nc2ccccc2Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O Show InChI InChI=1S/C43H45ClN8O8/c1-24-11-13-26(14-12-24)19-34(39(45)56)49-42(59)37(22-38(54)55)51-40(57)35(20-27-15-17-29(18-16-27)48-43(60)52-33-10-6-4-8-31(33)44)50-41(58)36(47-25(2)53)21-28-23-46-32-9-5-3-7-30(28)32/h3-18,23,34-37,46H,19-22H2,1-2H3,(H2,45,56)(H,47,53)(H,49,59)(H,50,58)(H,51,57)(H,54,55)(H2,48,52,60)/t34-,35?,36+,37+/m1/s1	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Antagonist activity against CCK-8 induced responses in guinea pig gall bladder was determined				J Med Chem 38: 207-11 (1995) BindingDB Entry DOI: 10.7270/Q28C9XF9
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50407328 (CHEMBL302150) Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(Cc1ccc(NC(=O)Nc2ccccc2Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(C)cc1)C(N)=O Show InChI InChI=1S/C43H45ClN8O8/c1-24-11-13-26(14-12-24)19-34(39(45)56)49-42(59)37(22-38(54)55)51-40(57)35(20-27-15-17-29(18-16-27)48-43(60)52-33-10-6-4-8-31(33)44)50-41(58)36(47-25(2)53)21-28-23-46-32-9-5-3-7-30(28)32/h3-18,23,34-37,46H,19-22H2,1-2H3,(H2,45,56)(H,47,53)(H,49,59)(H,50,58)(H,51,57)(H,54,55)(H2,48,52,60)/t34-,35?,36+,37+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Displacement of CCK-8 from CHO cell membranes expressing human Cholecystokinin type A receptor				J Med Chem 38: 207-11 (1995) BindingDB Entry DOI: 10.7270/Q28C9XF9
					More data for this Ligand-Target Pair