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SMILES: COc1ccc-2c(c1)C(CCc1cc(OC)c(OC)c(OC)c-21)NC(C)=O

InChI Key: InChIKey=FEPNCXXZWLXIHV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409021   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin alpha-1A chain


(Sus scrofa (Pig))		BDBM50409021
PNG
(CHEMBL52534)
Show SMILES COc1ccc-2c(c1)C(CCc1cc(OC)c(OC)c(OC)c-21)NC(C)=O
Show InChI InChI=1S/C21H25NO5/c1-12(23)22-17-9-6-13-10-18(25-3)20(26-4)21(27-5)19(13)15-8-7-14(24-2)11-16(15)17/h7-8,10-11,17H,6,9H2,1-5H3,(H,22,23)
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PubMed
n/an/a 1.51E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization interacting at the colchicine binding site.

J Med Chem 43: 167-76 (2000)


BindingDB Entry DOI: 10.7270/Q2CV4JZB
More data for this
Ligand-Target Pair