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BDBM50409612 CHEMBL2112006

SMILES: CN1CCc2c(-c3ccccc3)n(C)c3cccc(C1=O)c23

InChI Key: InChIKey=JBBHEUQXGHYOGK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409612   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50409612
PNG
(CHEMBL2112006)
Show SMILES CN1CCc2c(-c3ccccc3)n(C)c3cccc(C1=O)c23
Show InChI InChI=1S/C19H18N2O/c1-20-12-11-14-17-15(19(20)22)9-6-10-16(17)21(2)18(14)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibitory activity towards human poly(ADP-ribose) polymerase 1 (PARP-1).

J Med Chem 45: 4961-74 (2002)


BindingDB Entry DOI: 10.7270/Q2T152ZP
More data for this
Ligand-Target Pair