BDBM50409770 CHEMBL153067

SMILES: C(Cc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1)NCCc1ccccn1

InChI Key: InChIKey=WCRVDPZNPCPPJZ-UHFFFAOYSA-N

Data: 4 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50409770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Cavia porcellus)	BDBM50409770 (CHEMBL153067) Show SMILES C(Cc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1)NCCc1ccccn1 Show InChI InChI=1S/C27H30N4/c1-3-9-22(10-4-1)26(23-11-5-2-6-12-23)14-15-27-30-21-25(31-27)17-20-28-19-16-24-13-7-8-18-29-24/h1-13,18,21,26,28H,14-17,19-20H2,(H,30,31)	MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami...				J Med Chem 46: 5458-70 (2003) Article DOI: 10.1021/jm0309147 BindingDB Entry DOI: 10.7270/Q2CN753N
					More data for this Ligand-Target Pair
HRH3 (GUINEA PIG)	BDBM50409770 (CHEMBL153067) Show SMILES C(Cc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1)NCCc1ccccn1 Show InChI InChI=1S/C27H30N4/c1-3-9-22(10-4-1)26(23-11-5-2-6-12-23)14-15-27-30-21-25(31-27)17-20-28-19-16-24-13-7-8-18-29-24/h1-13,18,21,26,28H,14-17,19-20H2,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>501	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Tetsed for Antagonistic activity at histamine H3 receptor in guinea pig ileal longitudinal muscle in the presence of mepyramine at a concentration of...				J Med Chem 46: 5458-70 (2003) Article DOI: 10.1021/jm0309147 BindingDB Entry DOI: 10.7270/Q2CN753N
					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50409770 (CHEMBL153067) Show SMILES C(Cc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1)NCCc1ccccn1 Show InChI InChI=1S/C27H30N4/c1-3-9-22(10-4-1)26(23-11-5-2-6-12-23)14-15-27-30-21-25(31-27)17-20-28-19-16-24-13-7-8-18-29-24/h1-13,18,21,26,28H,14-17,19-20H2,(H,30,31)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	10.5	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Apparent pA2 value of compound at 50 nM concentration of mepyramine in rat aorta				J Med Chem 46: 5458-70 (2003) Article DOI: 10.1021/jm0309147 BindingDB Entry DOI: 10.7270/Q2CN753N
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50409770 (CHEMBL153067) Show SMILES C(Cc1cnc(CCC(c2ccccc2)c2ccccc2)[nH]1)NCCc1ccccn1 Show InChI InChI=1S/C27H30N4/c1-3-9-22(10-4-1)26(23-11-5-2-6-12-23)14-15-27-30-21-25(31-27)17-20-28-19-16-24-13-7-8-18-29-24/h1-13,18,21,26,28H,14-17,19-20H2,(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.37	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Apparent pA2 value of compound at 10 nM concentration of mepyramine in guinea pig ileum				J Med Chem 46: 5458-70 (2003) Article DOI: 10.1021/jm0309147 BindingDB Entry DOI: 10.7270/Q2CN753N
					More data for this Ligand-Target Pair