BDBM50409857 CHEMBL339347

SMILES: Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc1nc2ccccc2nc1-c1ccc(Cl)cc1

InChI Key: InChIKey=LPXHZSBXBCYGMB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50409857 (CHEMBL339347) Show SMILES Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc1nc2ccccc2nc1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H15Cl2N3O2S2/c1-12-10-19(18(29)11-15(12)23)30(27,28)26-21-20(13-6-8-14(22)9-7-13)24-16-4-2-3-5-17(16)25-21/h2-11,29H,1H3,(H,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory activity against 3' processing by HIV integrase				J Med Chem 47: 385-99 (2004) Article DOI: 10.1021/jm030378i BindingDB Entry DOI: 10.7270/Q2M61MFX
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50409857 (CHEMBL339347) Show SMILES Cc1cc(c(S)cc1Cl)S(=O)(=O)Nc1nc2ccccc2nc1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H15Cl2N3O2S2/c1-12-10-19(18(29)11-15(12)23)30(27,28)26-21-20(13-6-8-14(22)9-7-13)24-16-4-2-3-5-17(16)25-21/h2-11,29H,1H3,(H,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory activity against DNA strand transfer by HIV integrase				J Med Chem 47: 385-99 (2004) Article DOI: 10.1021/jm030378i BindingDB Entry DOI: 10.7270/Q2M61MFX
					More data for this Ligand-Target Pair