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SMILES: Cc1cc(C)c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)NC3(CCCC3)C(=O)N3CCN(CC3)C(=O)[C@@H](N)CC[N+](C)(C)C)c2n1

InChI Key: InChIKey=HJPYQPWVTVOICU-NDEPHWFRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411264   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50411264
PNG
(CHEMBL376866)
Show SMILES Cc1cc(C)c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)NC3(CCCC3)C(=O)N3CCN(CC3)C(=O)[C@@H](N)CC[N+](C)(C)C)c2n1
Show InChI InChI=1S/C35H47Cl2N6O5S/c1-23-21-24(2)39-32-25(23)9-8-10-29(32)48-22-26-27(36)11-12-30(31(26)37)49(46,47)40-35(14-6-7-15-35)34(45)42-18-16-41(17-19-42)33(44)28(38)13-20-43(3,4)5/h8-12,21,28,40H,6-7,13-20,22,38H2,1-5H3/q+1/t28-/m0/s1
PDB

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Similars
Article
PubMed
n/an/an/a 2n/an/an/an/an/a



Menarini Ricerche

Curated by ChEMBL


Assay Description
Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cells

J Med Chem 50: 550-65 (2007)


Article DOI: 10.1021/jm061143k
BindingDB Entry DOI: 10.7270/Q2H13374
More data for this
Ligand-Target Pair