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SMILES: CN1CCC(CC1)(NS(=O)(=O)c1ccc(Cl)c(COc2cccc3c(C)cc(C)nc23)c1Cl)C(=O)N1CCN(CC1)C(=O)[C@@H](N)CCC[N+](C)(C)C

InChI Key: InChIKey=WJEPXRSGCSZBGV-PMERELPUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411268   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50411268
PNG
(CHEMBL373607)
Show SMILES CN1CCC(CC1)(NS(=O)(=O)c1ccc(Cl)c(COc2cccc3c(C)cc(C)nc23)c1Cl)C(=O)N1CCN(CC1)C(=O)[C@@H](N)CCC[N+](C)(C)C
Show InChI InChI=1S/C37H52Cl2N7O5S/c1-25-23-26(2)41-34-27(25)9-7-11-31(34)51-24-28-29(38)12-13-32(33(28)39)52(49,50)42-37(14-16-43(3)17-15-37)36(48)45-20-18-44(19-21-45)35(47)30(40)10-8-22-46(4,5)6/h7,9,11-13,23,30,42H,8,10,14-22,24,40H2,1-6H3/q+1/t30-/m0/s1
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UniChem

Similars
Article
PubMed
n/an/an/a 0.251n/an/an/an/an/a



Menarini Ricerche

Curated by ChEMBL


Assay Description
Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cells

J Med Chem 50: 550-65 (2007)


Article DOI: 10.1021/jm061143k
BindingDB Entry DOI: 10.7270/Q2H13374
More data for this
Ligand-Target Pair