BindingDB logo
myBDB logout

null

SMILES: Cc1cc(C)c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)NC3(CCCC3)C(=O)N3CCN(CC3)C(=O)C[N+](C)(C)C)c2n1

InChI Key: InChIKey=SZUYSSJXWHWXNT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411273   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B2 bradykinin receptor


(Homo sapiens (Human))		BDBM50411273
PNG
(CHEMBL415152)
Show SMILES Cc1cc(C)c2cccc(OCc3c(Cl)ccc(c3Cl)S(=O)(=O)NC3(CCCC3)C(=O)N3CCN(CC3)C(=O)C[N+](C)(C)C)c2n1
Show InChI InChI=1S/C33H42Cl2N5O5S/c1-22-19-23(2)36-31-24(22)9-8-10-27(31)45-21-25-26(34)11-12-28(30(25)35)46(43,44)37-33(13-6-7-14-33)32(42)39-17-15-38(16-18-39)29(41)20-40(3,4)5/h8-12,19,37H,6-7,13-18,20-21H2,1-5H3/q+1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 5.01n/an/an/an/an/a



Menarini Ricerche

Curated by ChEMBL


Assay Description
Antagonist potency at human bradykinin B2 receptor assessed as effect on inositol monophosphate accumulation in CHOdhfr- cells

J Med Chem 50: 550-65 (2007)


Article DOI: 10.1021/jm061143k
BindingDB Entry DOI: 10.7270/Q2H13374
More data for this
Ligand-Target Pair