BDBM50411926 CHEMBL403215

SMILES: CC(C)(C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O)c1ccc(cn1)C#N

InChI Key: InChIKey=ZTAWWPCARCIRRE-ZCHFLCOESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50411926 (CHEMBL403215) Show SMILES CC(C)(C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O)c1ccc(cn1)C#N |wU:6.5,wD:13.18,TLB:5:6:14.9.10:12,6:7:14:10.11.12,THB:8:9:12:15.7.6,8:7:14.9.10:12,6:11:14:15.8.7,(2.38,-1.41,;1.6,-.09,;.77,1.23,;.29,-.91,;.35,-2.46,;-1.08,-.2,;-2.38,-1.02,;-2.35,-2.54,;-3.32,-3.84,;-4.74,-3.32,;-4.79,-1.74,;-3.79,-.48,;-5.12,-1,;-5.07,-2.48,;-6.23,-3.78,;-3.73,-2.93,;-6.56,-2.07,;-7.65,-3.16,;-6.96,-.59,;2.91,.7,;4.24,-.09,;5.59,.67,;5.6,2.21,;4.26,3,;2.92,2.24,;6.94,2.96,;8.27,3.72,)| Show InChI InChI=1S/C21H26N4O2/c1-20(2,16-4-3-12(10-22)11-24-16)19(27)25-17-14-5-13-6-15(17)9-21(7-13,8-14)18(23)26/h3-4,11,13-15,17H,5-9H2,1-2H3,(H2,23,26)(H,25,27)/t13?,14?,15?,17-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1				Bioorg Med Chem Lett 18: 2479-90 (2008) Article DOI: 10.1016/j.bmcl.2008.02.042 BindingDB Entry DOI: 10.7270/Q2QC04Q0
					More data for this Ligand-Target Pair