BDBM50411930 CHEMBL257011

SMILES: CC(C)(Oc1ccc(Br)cn1)C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O

InChI Key: InChIKey=OVWCXNJONVXOBU-PFUGWSBSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50411930 (CHEMBL257011) Show SMILES CC(C)(Oc1ccc(Br)cn1)C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O |wU:14.14,wD:21.27,TLB:13:14:22.17.18:20,14:15:22:18.19.20,THB:16:17:20:23.15.14,16:15:22.17.18:20,14:19:22:23.16.15,(27.85,-18.03,;27.07,-16.72,;26.25,-15.4,;28.39,-15.91,;29.74,-16.65,;29.78,-18.2,;31.13,-18.93,;32.44,-18.13,;33.8,-18.86,;32.4,-16.58,;31.04,-15.85,;25.76,-17.54,;25.82,-19.08,;24.4,-16.82,;23.1,-17.64,;23.13,-19.16,;22.16,-20.46,;20.74,-19.94,;20.7,-18.36,;21.7,-17.1,;20.37,-17.62,;20.42,-19.1,;19.26,-20.4,;21.75,-19.55,;18.92,-18.69,;17.84,-19.77,;18.53,-17.21,)| Show InChI InChI=1S/C20H26BrN3O3/c1-19(2,27-15-4-3-14(21)10-23-15)18(26)24-16-12-5-11-6-13(16)9-20(7-11,8-12)17(22)25/h3-4,10-13,16H,5-9H2,1-2H3,(H2,22,25)(H,24,26)/t11?,12?,13?,16-,20-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.03	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1				Bioorg Med Chem Lett 18: 2479-90 (2008) Article DOI: 10.1016/j.bmcl.2008.02.042 BindingDB Entry DOI: 10.7270/Q2QC04Q0
					More data for this Ligand-Target Pair