BDBM50411944 CHEMBL255148

SMILES: CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@@H]1C2CCCC1C[C@H](C2)C(N)=O

InChI Key: InChIKey=VSBPAZLSKLWBGS-QODXQOHISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50411944 (CHEMBL255148) Show SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@@H]1C2CCCC1C[C@H](C2)C(N)=O |wD:14.14,21.25,THB:23:21:14:16.17.18,13:14:16.17.18:20.21.22,(25.58,-1.61,;24.79,-.3,;23.97,1.02,;26.1,.5,;27.46,-.23,;27.49,-1.78,;28.85,-2.51,;30.16,-1.71,;31.52,-2.44,;30.12,-.16,;28.77,.57,;23.49,-1.12,;23.55,-2.66,;22.12,-.4,;20.82,-1.22,;19.32,-1.19,;17.53,-1.53,;16.99,-.09,;18.15,-.69,;19.88,-.34,;19.64,1.34,;18.15,1.37,;19.05,.56,;16.72,1.93,;15.51,.97,;16.49,3.46,)| Show InChI InChI=1S/C20H27ClN2O3/c1-20(2,26-16-8-6-15(21)7-9-16)19(25)23-17-12-4-3-5-13(17)11-14(10-12)18(22)24/h6-9,12-14,17H,3-5,10-11H2,1-2H3,(H2,22,24)(H,23,25)/t12?,13?,14-,17+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21.9	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1				Bioorg Med Chem Lett 18: 2479-90 (2008) Article DOI: 10.1016/j.bmcl.2008.02.042 BindingDB Entry DOI: 10.7270/Q2QC04Q0
					More data for this Ligand-Target Pair