BDBM50412247 CHEMBL492639

SMILES: CCO\N=C\c1ccccc1OC(C)C1=NCCN1

InChI Key: InChIKey=BVWLLEDYRCHASI-LICLKQGHSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50412247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50412247 (CHEMBL492639) Show SMILES CCO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	339	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic Alpha-2C receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50412247 (CHEMBL492639) Show SMILES CCO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	417	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2A receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50412247 (CHEMBL492639) Show SMILES CCO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2B receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50412247 (CHEMBL492639) Show SMILES CCO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O2/c1-3-18-17-10-12-6-4-5-7-13(12)19-11(2)14-15-8-9-16-14/h4-7,10-11H,3,8-9H2,1-2H3,(H,15,16)/b17-10+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as stimulation of extracellular acidification				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair