BDBM50412334 CHEMBL525555

SMILES: COc1ccc(Br)cc1C1Sc2ccccc2NC1=O

InChI Key: InChIKey=MUKCXAYOUMEGBK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel subunit alpha-1 (Rattus norvegicus)	BDBM50412334 (CHEMBL525555) Show SMILES COc1ccc(Br)cc1C1Sc2ccccc2NC1=O Show InChI InChI=1S/C15H12BrNO2S/c1-19-12-7-6-9(16)8-10(12)14-15(18)17-11-4-2-3-5-13(11)20-14/h2-8,14H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Pisa Curated by ChEMBL					Assay Description Activation of large-conductance calcium-activated potassium channel-mediated vasorelaxation in endothelium-denuded normotensive Wistar rat thoracic a...				J Med Chem 51: 5085-92 (2008) Article DOI: 10.1021/jm701605f BindingDB Entry DOI: 10.7270/Q2R49S16
					More data for this Ligand-Target Pair