BDBM50413200 CHEMBL458826

SMILES: Cc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1)-n1cccn1

InChI Key: InChIKey=IUWGZVVHKXVJDV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413200 (CHEMBL458826) Show SMILES Cc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1)-n1cccn1 Show InChI InChI=1S/C23H19N7S/c1-16-15-17(29-11-2-8-26-29)3-4-20(16)28-12-6-18-21(5-9-24-22(18)28)30-13-7-19(27-30)23-25-10-14-31-23/h2-5,7-11,13-15H,6,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
					More data for this Ligand-Target Pair