BDBM50413202 CHEMBL458115

SMILES: Cc1cc(O)ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1

InChI Key: InChIKey=VPBAFPNBOIHJCC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413202 (CHEMBL458115) Show SMILES Cc1cc(O)ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1 Show InChI InChI=1S/C20H17N5OS/c1-13-12-14(26)2-3-17(13)24-9-5-15-18(4-7-21-19(15)24)25-10-6-16(23-25)20-22-8-11-27-20/h2-4,6-8,10-12,26H,5,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
					More data for this Ligand-Target Pair