BDBM50413205 CHEMBL459007

SMILES: CCc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1)C#N

InChI Key: InChIKey=SLDLUTCLYXWZCR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413205 (CHEMBL459007) Show SMILES CCc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1)C#N Show InChI InChI=1S/C22H18N6S/c1-2-16-13-15(14-23)3-4-19(16)27-10-6-17-20(5-8-24-21(17)27)28-11-7-18(26-28)22-25-9-12-29-22/h3-5,7-9,11-13H,2,6,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
					More data for this Ligand-Target Pair