BDBM50413211 CHEMBL456241

SMILES: N#Cc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1)-c1cccs1

InChI Key: InChIKey=IUBYARQITZJLPM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413211 (CHEMBL456241) Show SMILES N#Cc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-c1nccs1)-c1cccs1 Show InChI InChI=1S/C24H16N6S2/c25-15-17-14-16(22-2-1-12-31-22)3-4-20(17)29-10-6-18-21(5-8-26-23(18)29)30-11-7-19(28-30)24-27-9-13-32-24/h1-5,7-9,11-14H,6,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	851	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
					More data for this Ligand-Target Pair