BDBM50413229 CHEMBL514761

SMILES: Clc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-n1cccn1)C#N

InChI Key: InChIKey=HRFHGLUUYXBHLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413229 (CHEMBL514761) Show SMILES Clc1cc(ccc1N1CCc2c1nccc2-n1ccc(n1)-n1cccn1)C#N Show InChI InChI=1S/C20H14ClN7/c21-16-12-14(13-22)2-3-18(16)26-10-5-15-17(4-8-23-20(15)26)27-11-6-19(25-27)28-9-1-7-24-28/h1-4,6-9,11-12H,5,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
					More data for this Ligand-Target Pair