BDBM50413231 CHEMBL458353

SMILES: COc1ccc(c(C)c1)-n1ccc2c(cc(C)nc12)-n1ccc(n1)-c1nccs1

InChI Key: InChIKey=WEIVYTPGBWNIDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50413231 (CHEMBL458353) Show SMILES COc1ccc(c(C)c1)-n1ccc2c(cc(C)nc12)-n1ccc(n1)-c1nccs1 Show InChI InChI=1S/C22H19N5OS/c1-14-12-16(28-3)4-5-19(14)26-9-6-17-20(13-15(2)24-21(17)26)27-10-7-18(25-27)22-23-8-11-29-22/h4-13H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells by SPA				J Med Chem 51: 7273-86 (2009) Article DOI: 10.1021/jm800743q BindingDB Entry DOI: 10.7270/Q2TT4S62
					More data for this Ligand-Target Pair