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SMILES: CN1C(CC(CN2CCCCC2)C1=O)c1ccc(cc1)-c1ccccc1Cl

InChI Key: InChIKey=XBAVWVJRTJQHFI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413322   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50413322
PNG
(CHEMBL462236)
Show SMILES CN1C(CC(CN2CCCCC2)C1=O)c1ccc(cc1)-c1ccccc1Cl
Show InChI InChI=1S/C23H27ClN2O/c1-25-22(15-19(23(25)27)16-26-13-5-2-6-14-26)18-11-9-17(10-12-18)20-7-3-4-8-21(20)24/h3-4,7-12,19,22H,2,5-6,13-16H2,1H3
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Article
PubMed
n/an/an/an/a 126n/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant alpha7 nAChR expressed in rat GH3 cells by calcium influx assay

Bioorg Med Chem Lett 19: 1287-91 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.073
BindingDB Entry DOI: 10.7270/Q2GM875B
More data for this
Ligand-Target Pair