BDBM50413624 CHEMBL484732
SMILES: CCCN1CCO[C@H]2[C@H]1CCc1cc3CCNC(=O)c3cc21
InChI Key: InChIKey=TUSYNOYQWBWIFT-IAGOWNOFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50413624![]() (CHEMBL484732) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 38.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Displacement of [3H]spiperone form human cloned dopamine D3 receptor expressed in CHO cells | Bioorg Med Chem Lett 19: 2133-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.015 BindingDB Entry DOI: 10.7270/Q28W3FH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50413624![]() (CHEMBL484732) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Displacement of [3H]spiperone form human cloned dopamine D2L receptor expressed in CHO cells | Bioorg Med Chem Lett 19: 2133-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.015 BindingDB Entry DOI: 10.7270/Q28W3FH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50413624![]() (CHEMBL484732) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.68 | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Activation of human dopamine D3 receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation proximity assay | Bioorg Med Chem Lett 19: 2133-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.015 BindingDB Entry DOI: 10.7270/Q28W3FH9 | |||||||||||
More data for this Ligand-Target Pair |