null

SMILES: CC(C)(C)c1ccc(cc1)N1CCN(CCN2Cc3ccccc3C2)C1=O

InChI Key: InChIKey=ZQIADMORWXCKPH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50414415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414415 (CHEMBL564298) Show SMILES CC(C)(C)c1ccc(cc1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C23H29N3O/c1-23(2,3)20-8-10-21(11-9-20)26-15-14-25(22(26)27)13-12-24-16-18-6-4-5-7-19(18)17-24/h4-11H,12-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50414415 (CHEMBL564298) Show SMILES CC(C)(C)c1ccc(cc1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C23H29N3O/c1-23(2,3)20-8-10-21(11-9-20)26-15-14-25(22(26)27)13-12-24-16-18-6-4-5-7-19(18)17-24/h4-11H,12-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTP-gamma-S-based scintillation spectrometry				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414415 (CHEMBL564298) Show SMILES CC(C)(C)c1ccc(cc1)N1CCN(CCN2Cc3ccccc3C2)C1=O Show InChI InChI=1S/C23H29N3O/c1-23(2,3)20-8-10-21(11-9-20)26-15-14-25(22(26)27)13-12-24-16-18-6-4-5-7-19(18)17-24/h4-11H,12-17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay				Bioorg Med Chem Lett 19: 4011-3 (2009) Article DOI: 10.1016/j.bmcl.2009.06.028 BindingDB Entry DOI: 10.7270/Q2J67J55
					More data for this Ligand-Target Pair