BDBM50414535 CHEMBL549909

SMILES: Cc1cc(C)c(C)c(-c2nnc(NC(=O)c3ccc4OCCOc4c3)s2)c1C

InChI Key: InChIKey=ATHZSHXZRMFCBP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50414535 (CHEMBL549909) Show SMILES Cc1cc(C)c(C)c(-c2nnc(NC(=O)c3ccc4OCCOc4c3)s2)c1C Show InChI InChI=1S/C21H21N3O3S/c1-11-9-12(2)14(4)18(13(11)3)20-23-24-21(28-20)22-19(25)15-5-6-16-17(10-15)27-8-7-26-16/h5-6,9-10H,7-8H2,1-4H3,(H,22,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assay				Bioorg Med Chem Lett 19: 4292-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.074 BindingDB Entry DOI: 10.7270/Q2SQ90DS
					More data for this Ligand-Target Pair