BDBM50414539 CHEMBL557857

SMILES: Cc1cc(C)c(-c2nnc(NC(=O)c3cccc4OCCOc34)s2)c(C)c1

InChI Key: InChIKey=XHPPODJXHQJPEZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50414539 (CHEMBL557857) Show SMILES Cc1cc(C)c(-c2nnc(NC(=O)c3cccc4OCCOc34)s2)c(C)c1 Show InChI InChI=1S/C20H19N3O3S/c1-11-9-12(2)16(13(3)10-11)19-22-23-20(27-19)21-18(24)14-5-4-6-15-17(14)26-8-7-25-15/h4-6,9-10H,7-8H2,1-3H3,(H,21,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assay				Bioorg Med Chem Lett 19: 4292-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.074 BindingDB Entry DOI: 10.7270/Q2SQ90DS
					More data for this Ligand-Target Pair