null

SMILES: COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1

InChI Key: InChIKey=AQPYEVVJFZDJNJ-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50414580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50414580 (CHEMBL555744) Show SMILES COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-21-11-14-6-3-7-18(14)19-9-8-17(15(19)20)13-5-2-4-12(16)10-13/h2,4-5,10,14H,3,6-9,11H2,1H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Binding affinity to human DRD2 receptor by GTPgammaS binding assay				Bioorg Med Chem Lett 19: 5056-9 (2009) Article DOI: 10.1016/j.bmcl.2009.07.055 BindingDB Entry DOI: 10.7270/Q2PR7X7C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50414580 (CHEMBL555744) Show SMILES COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-21-11-14-6-3-7-18(14)19-9-8-17(15(19)20)13-5-2-4-12(16)10-13/h2,4-5,10,14H,3,6-9,11H2,1H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4799-801 (2009) Article DOI: 10.1016/j.bmcl.2009.06.043 BindingDB Entry DOI: 10.7270/Q2154J9T
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414580 (CHEMBL555744) Show SMILES COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-21-11-14-6-3-7-18(14)19-9-8-17(15(19)20)13-5-2-4-12(16)10-13/h2,4-5,10,14H,3,6-9,11H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 4799-801 (2009) Article DOI: 10.1016/j.bmcl.2009.06.043 BindingDB Entry DOI: 10.7270/Q2154J9T
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50414580 (CHEMBL555744) Show SMILES COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-21-11-14-6-3-7-18(14)19-9-8-17(15(19)20)13-5-2-4-12(16)10-13/h2,4-5,10,14H,3,6-9,11H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	79.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Binding affinity to human DRD3 receptor by GTPgammaS binding assay				Bioorg Med Chem Lett 19: 5056-9 (2009) Article DOI: 10.1016/j.bmcl.2009.07.055 BindingDB Entry DOI: 10.7270/Q2PR7X7C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414580 (CHEMBL555744) Show SMILES COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-21-11-14-6-3-7-18(14)19-9-8-17(15(19)20)13-5-2-4-12(16)10-13/h2,4-5,10,14H,3,6-9,11H2,1H3/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG				Bioorg Med Chem Lett 19: 5056-9 (2009) Article DOI: 10.1016/j.bmcl.2009.07.055 BindingDB Entry DOI: 10.7270/Q2PR7X7C
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414580 (CHEMBL555744) Show SMILES COC[C@@H]1CCCN1N1CCN(C1=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3O2/c1-21-11-14-6-3-7-18(14)19-9-8-17(15(19)20)13-5-2-4-12(16)10-13/h2,4-5,10,14H,3,6-9,11H2,1H3/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assay				Bioorg Med Chem Lett 19: 4799-801 (2009) Article DOI: 10.1016/j.bmcl.2009.06.043 BindingDB Entry DOI: 10.7270/Q2154J9T
					More data for this Ligand-Target Pair