BDBM50414846 CHEMBL575788

SMILES: Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3cnc(nc3C2)-c2ccccc2)CC1

InChI Key: InChIKey=LSEUGCSNKVUOIA-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50414846 (CHEMBL575788) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3cnc(nc3C2)-c2ccccc2)CC1 Show InChI InChI=1S/C27H25FN4O2/c28-20-6-7-21-25(14-20)34-31-26(21)18-8-10-32(11-9-18)16-17-12-23-22(24(33)13-17)15-29-27(30-23)19-4-2-1-3-5-19/h1-7,14-15,17-18H,8-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2 receptor				Bioorg Med Chem Lett 19: 6059-62 (2009) Article DOI: 10.1016/j.bmcl.2009.09.041 BindingDB Entry DOI: 10.7270/Q2M046P5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50414846 (CHEMBL575788) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3cnc(nc3C2)-c2ccccc2)CC1 Show InChI InChI=1S/C27H25FN4O2/c28-20-6-7-21-25(14-20)34-31-26(21)18-8-10-32(11-9-18)16-17-12-23-22(24(33)13-17)15-29-27(30-23)19-4-2-1-3-5-19/h1-7,14-15,17-18H,8-13,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human cloned 5HT2A receptor				Bioorg Med Chem Lett 19: 6059-62 (2009) Article DOI: 10.1016/j.bmcl.2009.09.041 BindingDB Entry DOI: 10.7270/Q2M046P5
					More data for this Ligand-Target Pair