BDBM50414973 CHEMBL572537

SMILES: O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1

InChI Key: InChIKey=IZCXWLUHLXSGCA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50414973 (CHEMBL572537) Show SMILES O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1 Show InChI InChI=1S/C24H29N3O2/c28-23(20-4-11-25-12-5-20)27-15-9-24(10-16-27)7-13-26(14-8-24)18-21-3-1-2-19-6-17-29-22(19)21/h1-5,11-12H,6-10,13-18H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human CCR8				J Med Chem 52: 7706-23 (2009) Article DOI: 10.1021/jm900713y BindingDB Entry DOI: 10.7270/Q2TH8NZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414973 (CHEMBL572537) Show SMILES O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1 Show InChI InChI=1S/C24H29N3O2/c28-23(20-4-11-25-12-5-20)27-15-9-24(10-16-27)7-13-26(14-8-24)18-21-3-1-2-19-6-17-29-22(19)21/h1-5,11-12H,6-10,13-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp method				J Med Chem 52: 7706-23 (2009) Article DOI: 10.1021/jm900713y BindingDB Entry DOI: 10.7270/Q2TH8NZP
					More data for this Ligand-Target Pair