BDBM50414984 CHEMBL566974

SMILES: O=C(N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1)c1ccncn1

InChI Key: InChIKey=XYXAYUQJAMPEPZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50414984 (CHEMBL566974) Show SMILES O=C(N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1)c1ccncn1 Show InChI InChI=1S/C27H30N4O2/c32-26(24-10-15-28-21-29-24)31-18-13-27(14-19-31)11-16-30(17-12-27)20-22-6-4-5-9-25(22)33-23-7-2-1-3-8-23/h1-10,15,21H,11-14,16-20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human CCR8				J Med Chem 52: 7706-23 (2009) Article DOI: 10.1021/jm900713y BindingDB Entry DOI: 10.7270/Q2TH8NZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414984 (CHEMBL566974) Show SMILES O=C(N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1)c1ccncn1 Show InChI InChI=1S/C27H30N4O2/c32-26(24-10-15-28-21-29-24)31-18-13-27(14-19-31)11-16-30(17-12-27)20-22-6-4-5-9-25(22)33-23-7-2-1-3-8-23/h1-10,15,21H,11-14,16-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiology				J Med Chem 52: 7706-23 (2009) Article DOI: 10.1021/jm900713y BindingDB Entry DOI: 10.7270/Q2TH8NZP
					More data for this Ligand-Target Pair