BDBM50414985 CHEMBL568503

SMILES: CC1(C)CCc2cc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccncn3)ccc2O1

InChI Key: InChIKey=NEHPVKVKVDQPOY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50414985 (CHEMBL568503) Show SMILES CC1(C)CCc2cc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccncn3)ccc2O1 Show InChI InChI=1S/C26H34N4O2/c1-25(2)7-5-21-17-20(3-4-23(21)32-25)18-29-13-8-26(9-14-29)10-15-30(16-11-26)24(31)22-6-12-27-19-28-22/h3-4,6,12,17,19H,5,7-11,13-16,18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human CCR8				J Med Chem 52: 7706-23 (2009) Article DOI: 10.1021/jm900713y BindingDB Entry DOI: 10.7270/Q2TH8NZP
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50414985 (CHEMBL568503) Show SMILES CC1(C)CCc2cc(CN3CCC4(CC3)CCN(CC4)C(=O)c3ccncn3)ccc2O1 Show InChI InChI=1S/C26H34N4O2/c1-25(2)7-5-21-17-20(3-4-23(21)32-25)18-29-13-8-26(9-14-29)10-15-30(16-11-26)24(31)22-6-12-27-19-28-22/h3-4,6,12,17,19H,5,7-11,13-16,18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiology				J Med Chem 52: 7706-23 (2009) Article DOI: 10.1021/jm900713y BindingDB Entry DOI: 10.7270/Q2TH8NZP
					More data for this Ligand-Target Pair