BDBM50415744 CHEMBL1087568

SMILES: CCCC[C@H](NC(=O)O[C@@H]1CN(CC1(C)C)C(=O)CCCc1ccccc1)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key: InChIKey=LKCFEUIPIOLFGA-DURWQBQJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50415744 (CHEMBL1087568) Show SMILES CCCC[C@H](NC(=O)O[C@@H]1CN(CC1(C)C)C(=O)CCCc1ccccc1)C(=O)C(=O)N[C@H](C)c1ccccc1 |r| Show InChI InChI=1S/C32H43N3O5/c1-5-6-19-26(29(37)30(38)33-23(2)25-17-11-8-12-18-25)34-31(39)40-27-21-35(22-32(27,3)4)28(36)20-13-16-24-14-9-7-10-15-24/h7-12,14-15,17-18,23,26-27H,5-6,13,16,19-22H2,1-4H3,(H,33,38)(H,34,39)/t23-,26+,27-/m1/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human cathepsin K				Eur J Med Chem 45: 667-81 (2010) Article DOI: 10.1016/j.ejmech.2009.11.010 BindingDB Entry DOI: 10.7270/Q29C6ZP1
					More data for this Ligand-Target Pair