BDBM50415752 CHEMBL1089046

SMILES: CCCC[C@H](NC(=O)O[C@@H]1CN(CC1(C)C)C(=O)c1ccno1)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key: InChIKey=CEZBWJXPHJBRKI-SLYNCCJLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50415752 (CHEMBL1089046) Show SMILES CCCC[C@H](NC(=O)O[C@@H]1CN(CC1(C)C)C(=O)c1ccno1)C(=O)C(=O)N[C@H](C)c1ccccc1 |r| Show InChI InChI=1S/C26H34N4O6/c1-5-6-12-19(22(31)23(32)28-17(2)18-10-8-7-9-11-18)29-25(34)35-21-15-30(16-26(21,3)4)24(33)20-13-14-27-36-20/h7-11,13-14,17,19,21H,5-6,12,15-16H2,1-4H3,(H,28,32)(H,29,34)/t17-,19+,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.91	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human cathepsin K				Eur J Med Chem 45: 667-81 (2010) Article DOI: 10.1016/j.ejmech.2009.11.010 BindingDB Entry DOI: 10.7270/Q29C6ZP1
					More data for this Ligand-Target Pair