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SMILES: Cn1ncc2c(Cl)c(cnc12)C(=O)NCc1ccccc1

InChI Key: InChIKey=NZWMGVYGGYAWCY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50415799
PNG
(CHEMBL1093352)
Show SMILES Cn1ncc2c(Cl)c(cnc12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C15H13ClN4O/c1-20-14-11(9-19-20)13(16)12(8-17-14)15(21)18-7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3,(H,18,21)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...

Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair