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SMILES: CCn1ncc2c(Cl)c(cnc12)C(=O)NC

InChI Key: InChIKey=RILOJFZTOPJYOG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415814   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50415814
PNG
(CHEMBL1094032)
Show SMILES CCn1ncc2c(Cl)c(cnc12)C(=O)NC
Show InChI InChI=1S/C10H11ClN4O/c1-3-15-9-6(5-14-15)8(11)7(4-13-9)10(16)12-2/h4-5H,3H2,1-2H3,(H,12,16)
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PC sid
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Similars
Article
PubMed
n/an/a>6.31E+3n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...

Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair